Vedolizumab-Induced Liver Injury
نویسندگان
چکیده
منابع مشابه
Chronic Cholestatic Liver Injury Attributable to Vedolizumab
Drug-induced liver injury is a rare but clinically important diagnosis. Vedolizumab is an α4β7 integrin inhibitor recently approved for use in patients with moderate-to-severe inflammatory bowel disease. Cases of hepatoxicity due to vedolizumab in the pre-marketing stage were rare, and all cases resolved upon drug withdrawal. We present here the first reported case of hepatotoxicity attributabl...
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BACKGROUND Lamivudine is a nucleoside analogue antiretroviral drug, known for its low toxicity at clinically prescribed dose. However, the toxicity or mechanism of toxicity and target tissue effects during prolonged administration of higher doses were hardly given sufficient laboratory attention. AIM The present work was designed to investigate the biochemical and histopathological changes in...
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1Office of Computational Science, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA 2Center of Pharmacology and Toxicology, Hannover Medical School, Hannover, Germany 3Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA 4Division of Bioinformatics and Biostatistics, National Center for Toxicological Research,...
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ژورنال
عنوان ژورنال: GE - Portuguese Journal of Gastroenterology
سال: 2020
ISSN: 2341-4545,2387-1954
DOI: 10.1159/000511644